SCHEMBL21395957

SCHEMBL21395957

Cc1cc(Cl)ccc1N(C)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.48
GAA P10253 2/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.40
NOX1 Q9Y5S8 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GPBAR1 Q8TDU6 1/20 0.38
TSHR P16473 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396005 0.83 CYP3A4 (0.45) FSCN1GAAKMT2AALDH1A1CYP3A4
SCHEMBL8233668 0.82 KMT2A (0.57) FSCN1GAAKMT2AALDH1A1CYP3A4
SCHEMBL30937283 0.78 FSCN1 (0.53) FSCN1GAAKMT2AALDH1A1GPBAR1
SCHEMBL28006668 0.77 TDP1 (0.46) KMT2AALDH1A1CYP3A4KDM4ETSHR
SCHEMBL11418710 0.76 ALDH1A1 (0.39) FSCN1GAAKMT2AALDH1A1CYP3A4
SCHEMBL3732744 0.76 ALDH1A1 (0.42) FSCN1GAAKMT2AALDH1A1CYP3A4
SCHEMBL21396202 0.74 HRH4 (0.39) KMT2AALDH1A1CYP3A4POLBMAPT
SCHEMBL28310640 0.74 FSCN1 (0.41) FSCN1GAAKMT2AALDH1A1CYP3A4
SCHEMBL25777944 0.74 FSCN1 (0.44) FSCN1GAAKMT2AALDH1A1TSHR
SCHEMBL6351894 0.72 RAPGEF4 (0.39) FSCN1GAAKMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183358-A2 WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2019-09-26 WO disclosed