SCHEMBL2139599

SCHEMBL2139599

C=CCN(CC=C)CC1COC(CN(CC=C)CC=C)CO1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458282 0.98 ALDH1A1 (0.40) ALDH1A1TDP1
SCHEMBL4742463 0.93 ALDH1A1 (0.40) ALDH1A1TDP1
Oxirane SCHEMBL11562647 0.91 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL5853281 0.84 ALDH1A1 (0.34) ALDH1A1TDP1
SCHEMBL22198078 0.81 ALDH1A1 (0.32) ALDH1A1
SCHEMBL31515452 0.80 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL16641041 0.78 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29214425 0.77 ALDH1A1 (0.43) ALDH1A1TDP1
SCHEMBL14224651 0.76 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL8899453 0.76 ALDH1A1 (0.56) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863388-B2 Preparation of functionalized cationic polymers and their application in personal care BASF SE (DE) 2011-01-04 US disclosed
EP-1948700-A2 PREPARATION OF FUNCTIONALIZED CATIONIC POLYMERS AND THEIR PREPARATION AND APPLICATION IN PERSONAL CARE Ciba Holding Inc. (CH) 2008-07-30 EP disclosed
US-20070185281-A1 Preparation of functionalized cationic polymers & their application in personal care BASF SE (DE) 2007-08-09 US disclosed
WO-2007054468-A2 PREPARATION OF FUNCTIONALIZED CATIONIC POLYMERS AND THEIR PREPARATION AND APPLICATION IN PERSONAL CARE CIBA HOLDING INC. (CH) 2007-05-18 WO disclosed
EP-1124862-B1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS CIBA SPEC CHEM WATER TREAT LTD (GB) 2004-10-13 EP disclosed
US-6323306-B1 ADDING TO AQUEOUS SOLUTION OF AN AMINE FUNCTIONALIZED CATIONIC BASE POLYMER CROSS-LINKING AGENT REACTIVE WITH PRIMARY, SECONDARY OR TERTIARY AMINES OF BASE POLYMER TO FORM HIGHER MOLECULAR WEIGHT POLYMER CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2001-11-27 US disclosed
EP-1124862-A1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-08-22 EP disclosed
WO-2000014124-A1 PREPARATION OF WATER-SOLUBLE CROSS-LINKED CATIONIC POLYMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-03-16 WO disclosed