Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.34 |
| ▸ | CLK1 | P49759 | 3/20 | 0.34 |
| ▸ | CLK2 | P49760 | 3/20 | 0.34 |
| ▸ | CLK3 | P49761 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396943 | 0.91 | HTT (0.39) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21396777 | 0.90 | HTT (0.40) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21396958 | 0.87 | HTT (0.39) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21396657 | 0.85 | PDE10A (0.38) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21397054 | 0.84 | NCOA3 (0.37) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21396774 | 0.82 | HTT (0.40) | HTTNCOA3DYRK1ACDK5CDK5R1 | |
| SCHEMBL21396741 | 0.81 | TGFBR1 (0.39) | DYRK1AGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL21397146 | 0.81 | CDK4 (0.35) | NCOA3DYRK1ACLK4GSK3BCYP11B2 | |
| SCHEMBL21396962 | 0.80 | CDK4 (0.35) | NCOA3DYRK1ACLK4GSK3BCYP11B2 | |
| SCHEMBL21396775 | 0.79 | HTT (0.41) | HTTNCOA3DYRK1ACDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190296247-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296247-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLC25A21, SLCO4C1, SLC18A1 | HTT 1128/4885NCOA3 1772/4885DYRK1A 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.