Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167390 | 0.86 | MAPT (0.56) | BPTFCXCR4LMNAMAPTALOX12 | |
| Hydrochloric Acid SCHEMBL4185133 | 0.84 | MAPT (0.54) | BPTFCXCR4LMNAMAPTALOX12 | |
| SCHEMBL4168468 | 0.83 | LMNA (0.44) | LMNAMAPTALOX12SMN1; SMN2L3MBTL1 | |
| SCHEMBL23901548 | 0.80 | MAPT (0.48) | BPTFCXCR4LMNAMAPTALOX12 | |
| SCHEMBL31320012 | 0.79 | NOTUM (0.45) | BPTFCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21397270 | 0.78 | CHRM4 (0.49) | BPTFSUV39H2DPP4 | |
| SCHEMBL22655589 | 0.77 | NOTUM (0.46) | BPTFCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL22655484 | 0.77 | NOTUM (0.46) | BPTFCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL22680293 | 0.77 | NOTUM (0.46) | BPTFCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30656691 | 0.77 | NOTUM (0.46) | BPTFCHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |