Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167390 | 0.87 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL4185133 | 0.86 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL25453962 | 0.82 | BPTF (0.41) | MAPTSMN1; SMN2L3MBTL1LMNABPTF | |
| SCHEMBL23901733 | 0.82 | MAPT (0.51) | MAPTALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL21396910 | 0.80 | BPTF (0.50) | MAPTSMN1; SMN2L3MBTL1LMNABPTF | |
| SCHEMBL12505446 | 0.78 | HTR3E (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13182959 | 0.78 | ADRB1 (0.48) | MAPTL3MBTL1MEN1KMT2ABPTF | |
| SCHEMBL27606543 | 0.77 | ADRB1 (0.54) | MAPTALDH1A1SMN1; SMN2BPTFMAPK1 | |
| SCHEMBL8264511 | 0.76 | MAPT (0.68) | MAPTALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL7410614 | 0.75 | ALDH1A1 (0.62) | MAPTALDH1A1GFERSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021202600-A1 | SMALL MOLECULE INHIBITORS OF INFLUENZA HEMAGGLUTININ | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-07 | — | — | WO | disclosed |