SCHEMBL21396968

SCHEMBL21396968

N#Cc1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)c(-c2cccnc2-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
PTGER4 P35408 2/20 0.32
BRD4 O60885 2/20 0.31
HRH1 P35367 1/20 0.31
HTR6 P50406 1/20 0.31
EGFR P00533 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TNKS2 Q9H2K2 1/20 0.30
RORC P51449 1/20 0.30
ENPP3 O14638 1/20 0.30
GRM5 P41594 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396661 1.00 DDB1 (0.36) DDB1CRBNPTGER4BRD4HRH1
SCHEMBL21397014 0.93 DDB1 (0.37) DDB1CRBNPTGER4BRD4EGFR
SCHEMBL21397154 0.88 CSNK1A1 (0.36) DDB1CRBNPTGER4TNKS2GRM5
SCHEMBL21396688 0.88 DDB1 (0.34) DDB1CRBNPTGER4BRD4EGFR
SCHEMBL18374585 0.87 KDM4E (0.40) PTGER4KDM4EATML3MBTL1RORC
SCHEMBL21758352 0.87 DDB1 (0.36) DDB1CRBNPTGER4HRH1HTR6
SCHEMBL21758353 0.87 DDB1 (0.36) DDB1CRBNPTGER4HRH1HTR6
SCHEMBL26238194 0.86 KDM4E (0.37) PTGER4KDM4EATML3MBTL1RORC
SCHEMBL26304896 0.86 KDM4E (0.37) PTGER4KDM4EATML3MBTL1RORC
SCHEMBL22152953 0.85 KDM4E (0.36) PTGER4KDM4EATML3MBTL1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3543230-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-05-05 EP disclosed
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLC18A1 DDB1 2216/4885CRBN 4246/4885PTGER4 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.