SCHEMBL21758352

SCHEMBL21758352

N#Cc1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)c(-c2ncccc2-n2c3ccccc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
HRH1 P35367 1/20 0.33
HTR6 P50406 1/20 0.33
PTGER4 P35408 2/20 0.32
TNKS2 Q9H2K2 1/20 0.32
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
CCNA1 P78396 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31
EGFR P00533 1/20 0.31
TDO2 P48775 2/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21758353 1.00 DDB1 (0.36) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL21758229 0.93 DDB1 (0.40) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL21397011 0.92 PTGER4 (0.36) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL21758564 0.89 ATM (0.38) DDB1CRBNPTGER4CCNB2CDK1
SCHEMBL21758230 0.89 DDB1 (0.40) DDB1CRBNHRH1HTR6CCNB2
SCHEMBL21758517 0.88 TDO2 (0.38) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL21758187 0.88 IDO1 (0.37) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL21758351 0.87 TDO2 (0.36) DDB1CRBNHRH1HTR6PTGER4
SCHEMBL18374585 0.87 KDM4E (0.40) PTGER4KDM4EATML3MBTL1RORC
SCHEMBL21396968 0.87 DDB1 (0.36) DDB1CRBNHRH1HTR6PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3638749-B1 ORGANIC MOLECULE, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-05-19 EP disclosed
US-20200062734-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062734-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OXER1, OR10J3, OXGR1 DDB1 2347/4885CRBN 444/4885HRH1 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.