Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435954 | 0.86 | ALDH1A1 (0.47) | CKS1BSKP1SKP2ALDH1A1DRD2 | |
| SCHEMBL15759214 | 0.86 | CKS1B (0.47) | ACACBCKS1BSKP1SKP2DRD2 | |
| SCHEMBL3212610 | 0.86 | CKS1B (0.47) | CKS1BSKP1SKP2ALDH1A1DRD2 | |
| SCHEMBL30783037 | 0.86 | CKS1B (0.47) | CKS1BSKP1SKP2ALDH1A1DRD2 | |
| SCHEMBL31653702 | 0.85 | CKS1B (0.47) | CKS1BSKP1SKP2ALDH1A1DRD2 | |
| SCHEMBL13229631 | 0.85 | CKS1B (0.47) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL10264448 | 0.83 | DRD2 (0.48) | CKS1BSKP1SKP2DRD2DRD3 | |
| SCHEMBL4439231 | 0.83 | MAPT (0.55) | ALDH1A1 | |
| SCHEMBL31318667 | 0.82 | SUV39H2 (0.51) | DRD2SUV39H2PIM1PIM3PIM2 | |
| SCHEMBL17557723 | 0.82 | MAPT (0.56) | CKS1BSKP1SKP2ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |