Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 10/20 | 0.45 |
| ▸ | CDK9 | P50750 | 9/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.45 |
| ▸ | CCNH | P51946 | 5/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | MAPK6 | Q16659 | 6/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665608 | 1.00 | CDK1 (0.45) | CDK1KDRCDK7CDK9CCNT1 | |
| SCHEMBL16665607 | 0.78 | BTK (0.43) | CDK1KDRCDK7CDK9CCNH | |
| SCHEMBL21397323 | 0.78 | BTK (0.43) | CDK1KDRCDK7CDK9CCNH | |
| SCHEMBL21397410 | 0.78 | CDK7 (0.45) | CDK7CDK9CCNT1CCNHCSNK1A1 | |
| SCHEMBL16665651 | 0.78 | CDK7 (0.45) | CDK7CDK9CCNT1CCNHCSNK1A1 | |
| SCHEMBL16665691 | 0.74 | CCNT1 (0.49) | CDK7CDK9CCNT1CCNHCSNK1A1 | |
| SCHEMBL18074078 | 0.74 | CCNT1 (0.49) | CDK7CDK9CCNT1CCNHCSNK1A1 | |
| SCHEMBL18074046 | 0.74 | CCNK (0.49) | CDK1CDK2CCNE1CDK5CDK5R1 | |
| SCHEMBL23153437 | 0.73 | CDK7 (0.54) | CDK7CDK9CCNT1CCNHCSNK1A1 | |
| SCHEMBL21397211 | 0.72 | CCNT1 (0.49) | CDK7CDK9CCNT1CCNHCSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292167-A1 | HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | SYROS PHARMACEUTICALS INC (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292167-A1 | HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CDK7, CDK3, CDK17 | CDK1 6/4885KDR 714/4885CDK7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.