Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320283 | 0.78 | SMN1; SMN2 (0.52) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL7044034 | 0.78 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13320281 | 0.74 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL15723253 | 0.74 | MAPT (0.61) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL1031002 | 0.74 | ALDH1A1 (0.43) | MAPTTDP1KDM4EMEN1KMT2A | |
| SCHEMBL21397389 | 0.73 | MAPT (0.46) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL15725684 | 0.73 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL18390948 | 0.73 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL21397724 | 0.71 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL29012584 | 0.71 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019181714-A1 | COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME | 国立大学法人広島大学 | 2019-09-26 | — | — | WO | disclosed |