Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397389 | 0.97 | MAPT (0.46) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL22914740 | 0.88 | LMNA (0.46) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL21397726 | 0.86 | NR1H4 (0.43) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL21397725 | 0.86 | NPC1 (0.46) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL29895062 | 0.84 | MAPT (0.59) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL7050772 | 0.84 | MAPT (0.59) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL29012584 | 0.83 | MAPT (0.47) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL184114 | 0.82 | ALDH1A1 (0.43) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL21397390 | 0.80 | CYP2D6 (0.47) | MAPTSMN1; SMN2NPSR1RAB9ANPC1 | |
| SCHEMBL21397661 | 0.79 | CYP2C19 (0.40) | MAPTSMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019181714-A1 | COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME | 国立大学法人広島大学 | 2019-09-26 | — | — | WO | disclosed |