Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554150 | 0.84 | ACE (0.35) | ACEKMT2A | |
| SCHEMBL12648596 | 0.84 | ACE (0.35) | ACEKMT2A | |
| SCHEMBL8633574 | 0.84 | ACE (0.35) | ACEKMT2A | |
| SCHEMBL25995915 | 0.78 | KMT2A (0.33) | KMT2A | |
| SCHEMBL24882685 | 0.71 | ACE (0.38) | ACE | |
| SCHEMBL10308857 | 0.71 | ACE (0.34) | ACE | |
| SCHEMBL8903612 | 0.70 | KMT2A (0.38) | ACEPER2KMT2A | |
| SCHEMBL25668851 | 0.69 | L3MBTL1 (0.36) | KMT2A | |
| SCHEMBL12594212 | 0.68 | MAPT (0.37) | — | |
| SCHEMBL6940554 | 0.68 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752605-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190292163-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | CORSAIR PHARMA INC (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752605-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | ACE 156/4885PER2 2591/4885KMT2A 3480/4885 |
| US-20190292163-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | PTGIS, PTGIR, PTGER3 | ACE 156/4885PER2 2591/4885KMT2A 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.