Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21398001 | 1.00 | KDM4E (0.41) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL21397991 | 0.96 | DYRK1A (0.40) | DYRK1ACDK4CDK6AOC3KCNH2 | |
| SCHEMBL17349101 | 0.93 | DYRK1A (0.39) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL21397987 | 0.93 | ATM (0.41) | KDM4EATML3MBTL1RENKMT2A | |
| SCHEMBL21397974 | 0.93 | ATM (0.41) | KDM4EATML3MBTL1RENKMT2A | |
| SCHEMBL10029916 | 0.90 | MEN1 (0.42) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL21397986 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL126253 | 0.90 | L3MBTL1 (0.50) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL30367723 | 0.90 | L3MBTL1 (0.50) | KDM4EATML3MBTL1KMT2AMEN1 | |
| SCHEMBL30021164 | 0.90 | L3MBTL1 (0.50) | KDM4EATML3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179497-A1 | ORGANIC COMPOUND WITH PYRIDINE AS CORE AND USE THEREOF | 江苏三月光电科技有限公司 | 2019-09-26 | — | — | WO | disclosed |