SCHEMBL10029916

SCHEMBL10029916

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccncc6)c5c43)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 3/20 0.42
HSP90AA1 P07900 1/20 0.42
KDM4E B2RXH2 4/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TGFBR1 P36897 1/20 0.38
MAPK14 Q16539 1/20 0.38
ALDH1A1 P00352 3/20 0.38
USP2 O75604 2/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 4/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PDE5A O76074 2/20 0.36
PTGS1 P23219 1/20 0.36
TBXAS1 P24557 1/20 0.36
PTGS2 P35354 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021164 0.92 L3MBTL1 (0.50) MEN1KMT2AMAPTKDM4EATM
SCHEMBL126253 0.92 L3MBTL1 (0.50) MEN1KMT2AMAPTKDM4EATM
SCHEMBL30367723 0.92 L3MBTL1 (0.50) MEN1KMT2AMAPTKDM4EATM
SCHEMBL12288831 0.91 KMT2A (0.41) MEN1KMT2AMAPTHSP90AA1KDM4E
SCHEMBL23600614 0.90 L3MBTL1 (0.49) MEN1KMT2AMAPTKDM4EATM
SCHEMBL26052389 0.90 L3MBTL1 (0.44) MEN1KMT2AMAPTHSP90AA1KDM4E
SCHEMBL12691036 0.90 L3MBTL1 (0.49) MEN1KMT2AMAPTKDM4EATM
SCHEMBL12131847 0.90 L3MBTL1 (0.49) MEN1KMT2AMAPTKDM4EATM
SCHEMBL21397973 0.90 KDM4E (0.41) MEN1KMT2AMAPTHSP90AA1KDM4E
SCHEMBL21398001 0.90 KDM4E (0.41) MEN1KMT2AMAPTHSP90AA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-12035625-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
EP-4039774-B1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-09-20 EP disclosed
EP-3880682-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-14 EP disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120242217-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120223633-A1 ORGANIC EL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-09-06 US disclosed
US-20120112173-A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR PRODUCTION OF THE SAME SONY CORPORATION (JP) 2012-05-10 US disclosed
US-20120112173-A1 ORGANIC EL DISPLAY DEVICE AND METHOD FOR PRODUCTION OF THE SAME SONY CORPORATION (JP) 2012-05-10 US disclosed
US-8062769-B2 Indolocarbazole compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-11-22 US disclosed
US-8062769-B2 Indolocarbazole compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-11-22 US disclosed
US-20100187977-A1 COMPOUND FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2010-07-29 US disclosed
US-20100187977-A1 COMPOUND FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100187977-A1 COMPOUND FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE LAS1L, LEF1, OXA1L MEN1 2230/4885KMT2A 3202/4885MAPT 1603/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 MEN1 2301/4885KMT2A 4304/4885MAPT 1033/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 MEN1 2301/4885KMT2A 4304/4885MAPT 1033/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 MEN1 1112/4885KMT2A 2978/4885MAPT 1037/4885
US-12035625-B2 Materials for organic electroluminescent devices ZYX, RER1, AOC2 MEN1 1681/4885KMT2A 1372/4885MAPT 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.