SCHEMBL21398157

SCHEMBL21398157

Cc1ccc(-c2nc(-c3ccc(C)cc3)nc(C(C)C)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.50
RAB9A P51151 7/20 0.50
HTT P42858 2/20 0.50
CYP1A2 P05177 2/20 0.50
LMNA P02545 2/20 0.50
PTBP1 P26599 1/20 0.50
CYP2C19 P33261 1/20 0.50
TNFSF10 P50591 1/20 0.50
NPSR1 Q6W5P4 5/20 0.41
XBP1 P17861 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ADORA3 P0DMS8 2/20 0.39
ADORA1 P30542 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4110171 0.98 NPC1 (0.51) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL12311576 0.84 RAB9A (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL29325032 0.84 RAB9A (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL11810896 0.83 L3MBTL1 (0.52) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL6111135 0.83 L3MBTL1 (0.52) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL13231717 0.81 L3MBTL1 (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL2879894 0.81 L3MBTL1 (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL15025989 0.81 L3MBTL1 (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL2876376 0.81 L3MBTL1 (0.50) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL17563608 0.81 L3MBTL1 (0.54) NPC1RAB9AHTTLMNAXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019179497-A1 ORGANIC COMPOUND WITH PYRIDINE AS CORE AND USE THEREOF 江苏三月光电科技有限公司 2019-09-26 WO disclosed