Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357081 | 0.86 | HAO1 (0.55) | HAO1MAPTKMT2ACES2CES1 | |
| SCHEMBL12344752 | 0.83 | HAO1 (0.57) | HAO1MAPTKMT2ACES2CES1 | |
| SCHEMBL2755036 | 0.83 | HAO1 (0.57) | HAO1MAPTKMT2ACES2CES1 | |
| SCHEMBL18010753 | 0.82 | HAO1 (0.79) | HAO1MAPTKMT2ACES2FFAR4 | |
| SCHEMBL1712783 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 | |
| SCHEMBL5311427 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 | |
| SCHEMBL1080623 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 | |
| SCHEMBL5311779 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 | |
| SCHEMBL5307291 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 | |
| SCHEMBL10507922 | 0.82 | CES2 (0.64) | CES2FFAR4FFAR1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1776351-A1 | UV FILTER | MERCK PATENT GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018104-A1 | UV FILTER | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |
| US-3988446-A | Glycerides with anti-inflammatory properties | ABBOTT LABORATORIES (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038213-A1 | Uv Filters | ERCC4, ERCC1, ERCC5 | HAO1 2592/4885MAPT 1114/4885KMT2A 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.