Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755036 | 1.00 | HAO1 (0.57) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL31590747 | 0.98 | HAO1 (0.53) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL11685972 | 0.91 | HAO1 (0.45) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL27634581 | 0.89 | HAO1 (0.44) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL2357081 | 0.86 | HAO1 (0.55) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL7728958 | 0.85 | KMT2A (0.59) | HAO1KMT2AMAPTMEN1FAAH | |
| SCHEMBL2139864 | 0.83 | HAO1 (0.62) | HAO1KMT2AMAPTCES2CES1 | |
| SCHEMBL6269143 | 0.82 | CES2 (0.39) | HAO1KMT2AMEN1FAAHMAPK1 | |
| SCHEMBL23950131 | 0.82 | CES2 (0.64) | KMT2AMEN1FAAHMAPK1CES2 | |
| SCHEMBL23950441 | 0.82 | CES2 (0.64) | KMT2AMEN1FAAHMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279167-B1 | NOVEL PROCESS FOR THE PREPARATION OF 4-FLUORO-ALPHA-Ý2-METHYL -1-OXOPROPYL¨-GAMMA-OXO-N-ß-DIPHENYLBENZENEBUTANAMIDE AND PRODUCTS THEREFROM | ARCH PHARMALABS LTD (IN) | 2012-09-19 | — | — | EP | disclosed |