Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11654599 | 0.89 | SMN1; SMN2 (0.60) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1999857 | 0.89 | PDE7A (0.54) | MEN1KMT2AHTTPDE7AALDH1A1 | |
| SCHEMBL2814868 | 0.82 | PDE7A (0.44) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL589254 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AHTTPDE7AALDH1A1 | |
| SCHEMBL2718360 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL29618188 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AHTTPDE7AALDH1A1 | |
| SCHEMBL696354 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AHTTSMN1; SMN2PDE7A | |
| SCHEMBL2031510 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11997404 | 0.80 | SMN1; SMN2 (0.50) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30362286 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AHTTSMN1; SMN2PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290784-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290784-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | GFPT1, QPCT, GLB1 | MEN1 960/4885KMT2A 4015/4885HTT 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.