Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508627 | 0.75 | DRD2 (0.50) | HTR6GPR84DRD2SLC6A4MEN1 | |
| SCHEMBL1092992 | 0.74 | SLC6A4 (0.44) | GPR84DRD2SLC6A4MEN1KMT2A | |
| SCHEMBL2610331 | 0.74 | MEN1 (0.47) | MEN1KMT2ACDK2SNCA | |
| SCHEMBL2610330 | 0.74 | KMT2A (0.47) | GPR84MEN1KMT2AALDH1A1SNCA | |
| SCHEMBL21399614 | 0.73 | SLC5A2 (0.39) | HTR6GPR84SLC5A2ALDH1A1CHRM5 | |
| SCHEMBL2542209 | 0.71 | CDK2 (0.51) | HTR6GPR84DRD2SLC6A4MEN1 | |
| SCHEMBL29202637 | 0.71 | GPR84 (0.48) | GPR84SLC6A4ALDH1A1SCN9AKIF11 | |
| SCHEMBL2133199 | 0.71 | KMT2A (0.47) | MEN1KMT2AKDM4ESCN9AIDH1 | |
| SCHEMBL16597937 | 0.71 | HTR2A (0.61) | HTR6GPR84DRD2SLC6A4MEN1 | |
| Hydrochloric Acid SCHEMBL16598130 | 0.70 | HTR2A (0.59) | HTR6GPR84DRD2SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |