Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739463 | 1.00 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL26210082 | 1.00 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL8439903 | 1.00 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL27796739 | 1.00 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL13135047 | 1.00 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL9517595 | 0.97 | PIK3CD (0.42) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL9945700 | 0.88 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL9945703 | 0.88 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL9945705 | 0.88 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL17401248 | 0.88 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183523-A1 | HETERO-BIFUNCTIONAL DEGRADER COMPOUNDS AND THEIR USE AS MODULATORS OF TARGETED UBIQUINATION (VHL) | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |