Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26210082 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL8439903 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL27796739 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL15739463 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL21401554 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL13135047 | 0.97 | PIK3CD (0.41) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL42956 | 0.87 | ALDH1A1 (0.48) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL28088393 | 0.86 | ALDH1A1 (0.39) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL10389154 | 0.84 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 | |
| SCHEMBL4323031 | 0.84 | ALDH1A1 (0.46) | PIK3CDALDH1A1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401104-B1 | PROCESS FOR THE PREPARATION OF OPTICAL ISOMERS OF 2-CHLOROPROPIONIC ACID ESTERS | RHONE-POULENC CHIMIE (FR) | 1993-08-11 | — | — | EP | disclosed |
| EP-0401104-A1 | Process for the preparation of optical isomers of 2-chloropropionic acid esters | RHONE-POULENC CHIMIE (FR) | 1990-12-05 | — | — | EP | disclosed |