Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21402278 | 0.90 | TSHR (0.51) | CYP3A4TSHRNFKB1BCHETYR | |
| SCHEMBL21402286 | 0.86 | TSHR (0.55) | CYP3A4TSHRNFKB1BCHETYR | |
| SCHEMBL28550136 | 0.81 | CYP3A4 (0.67) | HTR1ACYP3A4TSHRNFKB1BLM | |
| SCHEMBL20467155 | 0.79 | HTR1A (0.58) | HTR1ACYP3A4TSHRNFKB1BCHE | |
| SCHEMBL10537953 | 0.78 | HTR1A (0.56) | HTR1ACYP3A4TSHRNFKB1BCHE | |
| SCHEMBL10661387 | 0.78 | HTR1A (0.56) | HTR1ACYP3A4TSHRNFKB1BCHE | |
| SCHEMBL20956603 | 0.77 | TSHR (0.53) | HTR1ACYP3A4TSHRNFKB1BCHE | |
| SCHEMBL21402272 | 0.77 | TSHR (0.55) | CYP3A4TSHRNFKB1BCHETYR | |
| SCHEMBL28410495 | 0.77 | TSHR (0.69) | HTR1ACYP3A4TSHRNFKB1BCHE | |
| SCHEMBL13561450 | 0.76 | TSHR (0.58) | CYP3A4TSHRNFKB1BCHETYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| EP-3275962-B1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2019-10-02 | — | — | EP | claimed |