Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | FOS | P01100 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21402278 | 0.89 | TSHR (0.51) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL21402269 | 0.86 | HTR1A (0.51) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL21402272 | 0.84 | TSHR (0.55) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL13561450 | 0.83 | TSHR (0.58) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL14960346 | 0.82 | TSHR (0.57) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL17295977 | 0.80 | TSHR (0.62) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL5072122 | 0.78 | BCHE (0.73) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL30491037 | 0.78 | BCHE (0.73) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL8082807 | 0.76 | TSHR (0.77) | TSHRCYP3A4NFKB1BLMPMP22 | |
| SCHEMBL29761292 | 0.76 | TSHR (0.77) | TSHRCYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| EP-3275962-B1 | METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2019-10-02 | — | — | EP | claimed |