Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.49 |
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21402684 | 0.84 | DDB1 (0.53) | CRBNDDB1ALDH1A1RPS6KA2ACHE | |
| SCHEMBL31623335 | 0.83 | CRBN (0.50) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL4937736 | 0.83 | CRBN (0.50) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL21402717 | 0.82 | DDB1 (0.50) | CRBNDDB1MAPTALDH1A1RPS6KA2 | |
| SCHEMBL31623352 | 0.82 | DDB1 (0.48) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL4940932 | 0.82 | DDB1 (0.48) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL14297668 | 0.80 | CRBN (0.44) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL4931124 | 0.80 | CRBN (0.53) | CRBNDDB1CASP1HSD17B10CASP7 | |
| SCHEMBL6755162 | 0.79 | DDB1 (0.31) | CRBNDDB1TNF | |
| SCHEMBL14294607 | 0.78 | CRBN (0.43) | CRBNDDB1CASP1HSD17B10CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873287-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | TIANJIN HEMAY PHARMACEUTICAL SCI-TECH CO., LTD (CN) | 2024-01-16 | — | — | US | claimed |
| US-20220372013-A2 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | GANZHOU HEMAY PHARMACEUTICAL, CO., LTD (CN) | 2022-11-24 | — | — | US | claimed |
| US-20220306600-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND ULCERATIVE COLITIS TREATING | TIANJIN HEMAY PHARMACEUTICAL SCI TECH CO LTD (CN) | 2022-09-29 | — | — | US | claimed |
| US-20190352277-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | TIANJIN HEMAY BIO TECH CO LTD (CN) | 2019-11-21 | — | — | US | claimed |
| EP-3546449-A1 | PIPERIDINE-2,6-DIKETONE DERIVATIVE AND TREATMENT FOR CROHN'S DISEASE | Tianjin Hemay Bio-Tech Co., Ltd (CN) | 2019-10-02 | — | — | EP | claimed |
| EP-3546450-A1 | PIPERIDINE-2,6-DIONE DERIVATIVE AND TREATMENT FOR ULCERATIVE COLITIS | Tianjin Hemay Bio-Tech Co., Ltd (CN) | 2019-10-02 | — | — | EP | claimed |
| US-12331030-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | TIANJIN HEMAY PHARMACEUTICAL SCI-TECH CO., LTD (CN) | 2025-06-17 | — | — | US | disclosed |
| US-20240132466-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND ULCERATIVE COLITIS TREATING | TIANJIN HEMAY PHARMACEUTICAL SCI TECH CO LTD (CN) | 2024-04-25 | — | — | US | disclosed |
| US-11873287-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | TIANJIN HEMAY PHARMACEUTICAL SCI-TECH CO., LTD (CN) | 2024-01-16 | — | — | US | disclosed |
| US-20220372013-A2 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | GANZHOU HEMAY PHARMACEUTICAL, CO., LTD (CN) | 2022-11-24 | — | — | US | disclosed |
| US-11485724-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | TIANJIN HEMAY PHARMACEUTICAL SCI-TECH CO., LTD (CN) | 2022-11-01 | — | — | US | disclosed |
| US-20220306600-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND ULCERATIVE COLITIS TREATING | TIANJIN HEMAY PHARMACEUTICAL SCI TECH CO LTD (CN) | 2022-09-29 | — | — | US | disclosed |
| US-20190352277-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | TIANJIN HEMAY BIO TECH CO LTD (CN) | 2019-11-21 | — | — | US | disclosed |
| EP-3546449-A1 | PIPERIDINE-2,6-DIKETONE DERIVATIVE AND TREATMENT FOR CROHN'S DISEASE | Tianjin Hemay Bio-Tech Co., Ltd (CN) | 2019-10-02 | — | — | EP | disclosed |
| EP-3546450-A1 | PIPERIDINE-2,6-DIONE DERIVATIVE AND TREATMENT FOR ULCERATIVE COLITIS | Tianjin Hemay Bio-Tech Co., Ltd (CN) | 2019-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132466-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND ULCERATIVE COLITIS TREATING | DPYD, PTGDR2, UCK2 | CRBN 3209/4885DDB1 3183/4885CASP1 1378/4885 |
| US-20190352277-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | PTGDR2, PTGDR, TPMT | CRBN 3060/4885DDB1 3702/4885CASP1 1590/4885 |
| US-12331030-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | DPYD, PTGDR2, UCK2 | CRBN 3209/4885DDB1 3183/4885CASP1 1378/4885 |
| US-11485724-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | DPYD, PTGDR2, UCK2 | CRBN 3209/4885DDB1 3183/4885CASP1 1378/4885 |
| US-11873287-B2 | Piperidine-2,6-dione derivatives and ulcerative colitis treating | DPYD, PTGDR2, UCK2 | CRBN 3209/4885DDB1 3183/4885CASP1 1378/4885 |
| US-20220372013-A2 | PIPERIDINE-2,6-DIONE DERIVATIVES AND CROHN'S DISEASE TREATING | PTGDR2, PTGDR, TPMT | CRBN 3060/4885DDB1 3702/4885CASP1 1590/4885 |
| US-20220306600-A1 | PIPERIDINE-2,6-DIONE DERIVATIVES AND ULCERATIVE COLITIS TREATING | DPYD, PTGDR2, UCK2 | CRBN 3209/4885DDB1 3183/4885CASP1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.