Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.42 |
| ▸ | PLG | P00747 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 6/20 | 0.38 |
| ▸ | HRH2 | P25021 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514642 | 0.87 | F2 (0.44) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL23202771 | 0.85 | KLKB1 (0.43) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL28529604 | 0.85 | F2 (0.48) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL28524886 | 0.85 | KLKB1 (0.41) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL21402735 | 0.84 | KLKB1 (0.43) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL21402769 | 0.83 | KLKB1 (0.40) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL21402740 | 0.83 | PLG (0.40) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL28516448 | 0.82 | F2 (0.46) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL28513705 | 0.81 | F2 (0.45) | KLKB1PLGPLAUF2PRSS1 | |
| SCHEMBL21402760 | 0.81 | PLG (0.40) | KLKB1PLGPLAUPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12151010-B2 | Skin lightening agent | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2024-11-26 | — | — | US | disclosed |
| EP-3804690-B1 | SKIN LIGHTENING AGENT | POLA CHEM IND INC (JP) | 2024-06-05 | — | — | EP | disclosed |
| CN-112135599-B | Skin whitening agent | 宝丽化成工业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-3545944-B1 | WRINKLE AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2022-12-28 | — | — | EP | disclosed |
| CN-114522115-A | Wrinkle-improving agent | 宝丽化成工业有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114288200-A | Wrinkle-improving agent | 宝丽化成工业有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-109996530-B | Wrinkle-improving agent | 宝丽化成工业有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-20210196599-A1 | SKIN LIGHTENING AGENT | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2021-07-01 | — | — | US | disclosed |
| EP-3804690-A1 | SKIN LIGHTENING AGENT | Pola Chemical Industries Inc. (JP) | 2021-04-14 | — | — | EP | disclosed |
| CN-112135599-A | Whitening agent | 宝丽化成工业有限公司 | 2020-12-25 | — | — | CN | disclosed |
| US-10835466-B2 | Wrinkle ameliorating agent | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2020-11-17 | — | — | US | disclosed |
| EP-3545944-A1 | WRINKLE AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2019-10-02 | — | — | EP | disclosed |
| CN-109996530-A | Wrinkle-improving agent | 宝丽化成工业有限公司 | 2019-07-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10835466-B2 | Wrinkle ameliorating agent | COL2A1, COL1A1, ACOX1 | ABL1 4366/4885KLKB1 4019/4885PLG 4464/4885 |
| US-20210196599-A1 | SKIN LIGHTENING AGENT | ACOX1, HAO1, CBR1 | ABL1 1041/4885KLKB1 3885/4885PLG 4515/4885 |
| US-12151010-B2 | Skin lightening agent | ACOX1, HAO1, CBR1 | ABL1 1041/4885KLKB1 3885/4885PLG 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.