Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 10/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9282116 | 0.99 | ALDH1A3 (0.53) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2141697 | 0.87 | ALDH1A1 (0.59) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2127391 | 0.87 | ALDH1A3 (0.66) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2128509 | 0.87 | ALDH1A1 (0.64) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| Bromide SCHEMBL9283397 | 0.86 | ALDH1A3 (0.60) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2129493 | 0.84 | ALDH1A1 (0.55) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2127074 | 0.84 | NPC1 (0.56) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2126827 | 0.84 | ALDH1A1 (0.65) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2127814 | 0.84 | NPC1 (0.57) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2127666 | 0.84 | NPC1 (0.62) | ALDH1A3ALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129375-B1 | IMIDAZO[1,2-A]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-04-25 | — | — | EP | claimed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |