SCHEMBL214066

SCHEMBL214066

C=C(C)C(=O)OC(CC)C1(C(CC)OC(=O)C(=C)C)CC[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727120 0.89
SCHEMBL757007 0.85
SCHEMBL10940323 0.82 LMNA (0.31)
SCHEMBL8994409 0.78
SCHEMBL10887307 0.77
SCHEMBL10888419 0.74
SCHEMBL3446227 0.73 ALDH1A1 (0.32)
SCHEMBL9566341 0.73
SCHEMBL4340354 0.73
SCHEMBL16859715 0.72 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 785 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2187243-B2 Colored ink for pad transfer printing of silicone hydrogel lenses ALCON INC (CH) 2025-07-09 EP claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
EP-3598181-B1 VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME ALCON INC (CH) 2021-06-23 EP claimed
EP-1648534-B2 ANTIMICROBIAL MEDICAL DEVICES NOVARTIS AG (CH) 2018-11-14 EP claimed
US-9880324-B2 Colored ink for pad transfer printing of silicone hydrogel lenses NOVARTIS AG (CH) 2018-01-30 US claimed
US-9612455-B2 Extended wear ophthalmic lens NOVARTIS AG (CH) 2017-04-04 US claimed
US-9322960-B2 Method of making a contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2016-04-26 US claimed
US-20150247956-A1 METHOD OF MAKING A CONTACT LENS COOPERVISION INTERNATIONAL LIMITED (GB) 2015-09-03 US claimed
US-20150076721-A1 COLORED INK FOR PAD TRANSFER PRINTING OF SILICONE HYDROGEL LENSES ALCON INC. (CH) 2015-03-19 US claimed
US-20050013842-A1 Antimicrobial medical devices ALCON INC. (CH) 2005-01-20 US claimed
US-20040246436-A1 Tinted, high Dk ophthalmic molding and a method for making same ALCON INC. (CH) 2004-12-09 US claimed
EP-0216074-B1 POLYVINYL ALCOHOL DERIVATIVES AND CROSSLINKED HYDROGEL CONTACT LENSES MADE THEREFROM CIBA-GEIGY AG (CH) 1993-06-16 EP claimed
US-4666249-A Surface-treated contact lens and method of producing SOLA U.S.A. INC. (US) 1987-05-19 US claimed
EP-0216074-A2 Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
EP-0174368-A1 SILICONE HYDRIDE CONTACT LENS AND POLYMER MC CARRY, John D. (US) 1986-03-19 EP claimed
WO-1985003940-A1 SILICONE HYDRIDE CONTACT LENS AND POLYMER MC CARRY, JOHN, D. (US) 1985-09-12 WO claimed
US-4507452-A HIGH OXYGEN PERMEABILITY, REDUCED TENDENCY FOR BIOLOGICAL CONTAMIN McCarry, John D. (US) 1985-03-26 US claimed
EP-0108886-A2 Silicone-containing hard contact lens materials having increased oxygen permeability CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
US-4400333-A Production of oxygen permeable contact lenses NEEFE OPTICAL LABORATORY 1983-08-23 US claimed