SCHEMBL21407976

SCHEMBL21407976

C=Cc1ccc(CN(CCCN(C)C)CCCN(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
HRH3 Q9Y5N1 4/20 0.41
ALDH1A1 P00352 2/20 0.38
PYCR1 P32322 1/20 0.34
KCNH2 Q12809 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
CALM1 P0DP23 1/20 0.34
CAMKK2 Q96RR4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21407960 0.89 CALM1 (0.42) MAPTHRH3ALDH1A1PYCR1HDAC3
SCHEMBL21407969 0.86 MAPT (0.46) MAPTHRH3
SCHEMBL21407986 0.85 HRH3 (0.44) HRH3ALDH1A1KCNH2
SCHEMBL611367 0.84 MAPT (0.61) MAPTHRH3ALDH1A1KCNH2
SCHEMBL14889187 0.83 MAPT (0.54) MAPTHRH3KCNH2
SCHEMBL696971 0.81 MAPT (0.53) MAPTHRH3KCNH2
SCHEMBL14889233 0.81 MAPT (0.53) MAPTHRH3KCNH2
SCHEMBL14889203 0.81 MAPT (0.53) MAPTHRH3KCNH2
SCHEMBL14889162 0.81 MAPT (0.53) MAPTHRH3KCNH2
SCHEMBL9989362 0.81 MAPT (0.40) MAPTHTTHRH3ALDH1A1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820847-B2 Copolymer, method of preparing the same, and rubber composition including the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-11-21 US claimed
US-20230192934-A1 COPOLYMER, METHOD OF PREPARING THE SAME, AND RUBBER COMPOSITION INCLUDING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-06-22 US claimed
US-11549003-B2 Copolymer, rubber composition, and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-01-10 US claimed
US-20200255635-A1 COPOLYMER, RUBBER COMPOSITION, AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-08-13 US claimed
US-11820847-B2 Copolymer, method of preparing the same, and rubber composition including the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-11-21 US disclosed
US-20230192934-A1 COPOLYMER, METHOD OF PREPARING THE SAME, AND RUBBER COMPOSITION INCLUDING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-06-22 US disclosed
US-11549003-B2 Copolymer, rubber composition, and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-01-10 US disclosed
US-11059929-B2 Copolymer including functional monomer and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2021-07-13 US disclosed
US-20200255635-A1 COPOLYMER, RUBBER COMPOSITION, AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-08-13 US disclosed
US-20190300638-A1 COPOLYMER INCLUDING FUNCTIONAL MONOMER AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2019-10-03 US disclosed