SCHEMBL21407960

SCHEMBL21407960

C=Cc1ccc(CN(CCN(C)C)CCN(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.42
CAMKK2 Q96RR4 1/20 0.42
HRH3 Q9Y5N1 5/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 2/20 0.37
PYCR1 P32322 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
KDM4E B2RXH2 2/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21407976 0.89 MAPT (0.42) CALM1CAMKK2HRH3ALDH1A1MAPT
SCHEMBL6390256 0.86 ALDH1A1 (0.50) HRH3ALDH1A1MAPTPYCR1KDM4E
SCHEMBL9679480 0.85 PYCR1 (0.43) HRH3ALDH1A1MAPTPYCR1HDAC3
SCHEMBL610061 0.83 HRH3 (0.62) HRH3ALDH1A1MAPTBCHE
SCHEMBL465236 0.82 HRH3 (0.56) HRH3ALDH1A1PYCR1HDAC3HDAC6
SCHEMBL18493213 0.82 ALDH1A1 (0.55) HRH3ALDH1A1MAPTPYCR1HDAC3
Hydrochloric Acid SCHEMBL1396391 0.80 HRH3 (0.54) HRH3ALDH1A1PYCR1HDAC3HDAC6
Ethane SCHEMBL6027727 0.80 HRH3 (0.54) HRH3ALDH1A1PYCR1HDAC3HDAC6
SCHEMBL6442857 0.80 HRH3 (0.52) HRH3ALDH1A1PYCR1HDAC3HDAC6
SCHEMBL611367 0.80 MAPT (0.61) HRH3ALDH1A1MAPTBCHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820847-B2 Copolymer, method of preparing the same, and rubber composition including the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-11-21 US claimed
US-20230192934-A1 COPOLYMER, METHOD OF PREPARING THE SAME, AND RUBBER COMPOSITION INCLUDING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-06-22 US claimed
US-11549003-B2 Copolymer, rubber composition, and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-01-10 US claimed
US-20200255635-A1 COPOLYMER, RUBBER COMPOSITION, AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-08-13 US claimed
US-11820847-B2 Copolymer, method of preparing the same, and rubber composition including the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-11-21 US disclosed
US-20230192934-A1 COPOLYMER, METHOD OF PREPARING THE SAME, AND RUBBER COMPOSITION INCLUDING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-06-22 US disclosed
US-11549003-B2 Copolymer, rubber composition, and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2023-01-10 US disclosed
US-11059929-B2 Copolymer including functional monomer and method of preparing the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2021-07-13 US disclosed
US-20200255635-A1 COPOLYMER, RUBBER COMPOSITION, AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-08-13 US disclosed
US-20190300638-A1 COPOLYMER INCLUDING FUNCTIONAL MONOMER AND METHOD OF PREPARING THE SAME KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2019-10-03 US disclosed