Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248772 | 0.79 | POLB (0.51) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL17173936 | 0.77 | POLB (0.68) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL8041064 | 0.75 | GSK3B (0.46) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL20550958 | 0.75 | KMT2A (0.43) | KMT2ALMNA | |
| SCHEMBL28272012 | 0.74 | POLB (0.49) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL17610383 | 0.74 | GSK3B (0.49) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL8888266 | 0.73 | CSF1R (0.66) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL13615359 | 0.73 | CYP1A2 (0.67) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL21711383 | 0.73 | GSK3B (0.44) | POLBKDRGSK3BCSF1RFGFR1 | |
| SCHEMBL27850030 | 0.72 | MAP2K1 (0.48) | POLBCLK4DYRK1BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019184918-A1 | 3-AMINOPYRAZOLE COMPOUND AND APPLICATION THEREOF | 暨南大学 | 2019-10-03 | — | — | WO | disclosed |