Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430781 | 0.82 | POLB (0.41) | POLBKMT2ACSNK1DCSNK1ESMN1; SMN2 | |
| SCHEMBL28930107 | 0.82 | POLB (0.41) | POLBCA1CA2KMT2AMEN1 | |
| SCHEMBL18691185 | 0.81 | POLB (0.40) | POLBCA1CA2KMT2AMEN1 | |
| SCHEMBL3232399 | 0.81 | POLB (0.40) | POLBCA1CA2KMT2AMEN1 | |
| SCHEMBL1763152 | 0.81 | CSNK1E (0.43) | POLBKDRFGFR1FLT1GSK3A | |
| SCHEMBL27708027 | 0.81 | SCN9A (0.41) | POLBNTRK1CSNK1DCSNK1ELMNA | |
| SCHEMBL1762881 | 0.80 | CSNK1D (0.41) | POLBLRRK2CSNK1DCSNK1ETP53 | |
| SCHEMBL1762883 | 0.80 | POLB (0.38) | POLBRETCSNK1DCSNK1EGRM5 | |
| SCHEMBL1762833 | 0.80 | PTGER4 (0.39) | POLBGAAGRM5 | |
| SCHEMBL3865439 | 0.80 | POLB (0.39) | POLBCA1CA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570018-A | Amide compound and preparation method and application thereof | 上海泰禾国际贸易有限公司 | 2018-09-25 | — | — | CN | disclosed |