Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SDHB | P21912 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747778 | 0.92 | POLB (0.51) | LMNAPOLBSDHBPKMMRGPRX4 | |
| SCHEMBL6638516 | 0.89 | LMNA (0.50) | TDP1L3MBTL1LMNAKAT6ACES1 | |
| SCHEMBL776559 | 0.89 | KMT2A (0.47) | KAT6APOLBPKMMAPTRAB9A | |
| SCHEMBL28679439 | 0.84 | PTPN1 (0.41) | TDP1CES1CES2MAPTRAB9A | |
| SCHEMBL9418408 | 0.82 | CES2 (0.49) | TDP1LMNAKAT6ACES1CES2 | |
| SCHEMBL28830274 | 0.79 | TSHR (0.46) | SRD5A2 | |
| SCHEMBL28573797 | 0.79 | PDCD1 (0.49) | L3MBTL1MAPTRAB9A | |
| SCHEMBL21408401 | 0.78 | MRGPRX4 (0.42) | LMNAPOLBF2MRGPRX4SRD5A2 | |
| SCHEMBL28564573 | 0.78 | CES2 (0.43) | ATMCES1CES2PKMMAPT | |
| SCHEMBL778826 | 0.76 | TDP1 (0.50) | ATMTDP1LMNACES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019185586-A1 | LIGANDS FOR ENHANCED IMAGING AND DRUG DELIVERY TO NEUROBLASTOMA CELLS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2019-10-03 | — | — | WO | disclosed |