1,6-Hexanediol

1,6-Hexanediol

SCHEMBL2140845

CC(O)C(C)O.OCCCCCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 1/20 0.41
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
TRPV1 Q8NER1 1/20 0.35
TRPA1 O75762 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MIF P14174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,5-Pentanediol SCHEMBL5410111 1.00 TSHR (0.50) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL10732844 0.96 SMN1; SMN2 (0.47) TSHRALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL28268811 0.89 TSHR (0.53) TSHRALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL9470728 0.87 TSHR (0.45) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL28251472 0.87 TDP1 (0.62) TSHRALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL18689351 0.87 TSHR (0.45) TSHRALDH1A1LMNAHSD17B10MEN1
1,5-Pentanediol SCHEMBL10532023 0.86 TSHR (0.47) TSHRALDH1A1LMNAHSD17B10MEN1
1,3-Propanediol SCHEMBL28201030 0.86 TDP1 (0.41) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL2293967 0.85 ALDH1A1 (0.50) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL973912 0.85 SMN1; SMN2 (0.50) TSHRALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511241-B Article and method of making an article comprising a coating 耐克创新有限合伙公司 2021-12-07 CN disclosed
EP-3085717-B1 LIQUID CRYSTALLINE POLYURETHANE ELASTOMER AND METHOD FOR PRODUCING SAME TOYO TIRE & RUBBER CO (JP) 2018-01-31 EP disclosed
EP-3085717-A1 LIQUID CRYSTALLINE POLYURETHANE ELASTOMER AND METHOD FOR PRODUCING SAME Toyo Tire & Rubber Co., Ltd. (JP) 2016-10-26 EP disclosed
EP-2986904-A1 IN MOLD ELECTRONIC PRINTED CIRCUIT BOARD ENCAPSULATION AND ASSEMBLY Covestro LLC (US) 2016-02-24 EP disclosed
WO-2014172411-A1 IN MOLD ELECTRONIC PRINTED CIRCUIT BOARD ENCAPSULATION AND ASSEMBLY BAYER MATERIALSCIENCE LLC (US) 2014-10-23 WO disclosed
US-8257153-B2 Polishing pad and a method for manufacturing the same TOYO TIRE & RUBBER CO., LTD. (JP) 2012-09-04 US disclosed
US-8148441-B2 Chain extension and curing of an isocyanate-terminated prepolymer with an aromatic diamine to produce a polyurethane foam with uniform, fine cells; improved dressability with maintained planarization characteristics and polishing speed; halogen-free TOYO TIRE & RUBBER CO., LTD. (JP) 2012-04-03 US disclosed
US-20100029185-A1 POLISHING PAD AND A METHOD FOR MANUFACTURING THE SAME TOYO TIRE & RUBBER CO., LTD. (JP) 2010-02-04 US disclosed
US-20080085943-A1 Polishing Pad and Manufacturing Method Thereof TOYO TIRE & RUBBER CO., LTD. (JP) 2008-04-10 US disclosed
US-4128512-A Post treatment of flexible polyurethane foam with organic siloxanes for increasing the water absorbency and penetration MOBAY CHEMICAL CORPORATION (US) 1978-12-05 US disclosed
US-4098731-A BASED ON POLYISOCYANATES; CARBOXYLIC ACID SALTS AND TERTIARY AMINES AS MOLD RELEASE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed