1,4-Butanediol

1,4-Butanediol

SCHEMBL2293967

CC(C)O.OCCCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 5/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
TRPA1 O75762 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL28268811 0.96 TSHR (0.53) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,4-Butanediol SCHEMBL973912 0.92 SMN1; SMN2 (0.50) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,3-Propanediol SCHEMBL8809902 0.92
1,4-Butanediol SCHEMBL10732844 0.88 SMN1; SMN2 (0.47) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,3-Propanediol SCHEMBL4960368 0.88 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1-Pentanol SCHEMBL6849410 0.87 SMN1; SMN2 (0.75) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
Hexane SCHEMBL28618120 0.87 SMN1; SMN2 (0.75) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,4-Butanediol SCHEMBL531424 0.85 TDP1 (0.71) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,4-Butanediol SCHEMBL28655257 0.85 TDP1 (0.71) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10
1,5-Pentanediol SCHEMBL5410111 0.85 TSHR (0.50) ALDH1A1LMNASMN1; SMN2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110195170-A1 COMPOSITIONS COMPRISING SWEETNESS ENHANCERS AND METHODS OF MAKING THEM SENOMYX INC. 2011-08-11 US claimed
US-4131698-A Pretreatment of polyvinyl chloride plastics for electroless deposition RCA CORPORATION (US) 1978-12-26 US claimed
EP-0956047-A1 NEW CARRIER SYSTEMS IPR-Institute for Pharmaceutical Research Riehen AG (CH) 1999-11-17 EP disclosed
WO-1998016251-A1 NEW CARRIER SYSTEMS IPR-INSTITUTE FOR PHARMACEUTICAL RESEARCH AG (CH) 1998-04-23 WO disclosed