Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28240025 | 0.96 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21801676 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL4303342 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL9561381 | 0.92 | — | — | |
| Alcohol SCHEMBL25399402 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL25333131 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21808784 | 0.92 | — | — | |
| Alcohol SCHEMBL21599246 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21297005 | 0.92 | TSHR (0.60) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL2039900 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184363-A | Preparation method and preparation system of nitride ceramic | 安徽壹石通材料科技股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-113213947-A | Aluminum nitride doped modified nano silicon nitride composite ceramic powder and preparation method thereof | 福建臻璟新材料科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-109006865-A | A kind of nano-filled particle and preparation method thereof | 上海沪正纳米科技有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106565232-A | Titanium dioxide gas sensitive film preparation method | 洛阳鼎威材料科技有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-118345439-A | Oxygen-evolving titanium anode and preparation method thereof | 广东省科学院资源利用与稀土开发研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-115236022-B | Method and system for characterizing and predicting flame synthesis characteristics of precursor | 清华大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-115151594-A | Polyester resin with little foreign matter and coating composition or adhesive composition using same | 东洋纺株式会社 | 2022-10-04 | — | — | CN | disclosed |
| CN-110327978-B | Preparation method of yttrium metal organic framework supported noble metal catalyst | 华侨大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113213947-A | Aluminum nitride doped modified nano silicon nitride composite ceramic powder and preparation method thereof | 福建臻璟新材料科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113166402-A | Semi-aromatic polyamide resin and method for producing same | 东洋纺株式会社 | 2021-07-23 | — | — | CN | disclosed |
| CN-110407597-B | Rare earth oxide modified silicon carbide ceramic matrix composite material and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-05-25 | — | — | CN | disclosed |
| CN-112204075-A | Semi-aromatic polyamide resin and method for producing same | 东洋纺株式会社 | 2021-01-08 | — | — | CN | disclosed |
| CN-110327978-A | A kind of preparation method of yttrium metal organic framework supported precious metal catalyst | 华侨大学 | 2019-10-15 | — | — | CN | disclosed |
| WO-2019189145-A1 | SEMI-AROMATIC POLYAMIDE RESIN AND METHOD FOR MANUFACTURING SAME | 東洋紡株式会社 | 2019-10-03 | — | — | WO | disclosed |
| CN-106084465-B | A kind of terres rares polypropylene reinforcement nucleating agent and preparation method thereof | 广东炜林纳新材料科技股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109006865-A | A kind of nano-filled particle and preparation method thereof | 上海沪正纳米科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-109006865-A | A kind of nano-filled particle and preparation method thereof | 上海沪正纳米科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-106565232-A | Titanium dioxide gas sensitive film preparation method | 洛阳鼎威材料科技有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106565232-A | Titanium dioxide gas sensitive film preparation method | 洛阳鼎威材料科技有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-106084465-A | A kind of terres rares polypropylene reinforcement nucleating agent and preparation method thereof | 广东炜林纳新材料科技股份有限公司 | 2016-11-09 | — | — | CN | disclosed |