Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28240025 | 0.96 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL2039900 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL4303342 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL3254817 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL25399402 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL25333131 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21801676 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21409712 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21808784 | 0.92 | — | — | |
| Alcohol SCHEMBL21599246 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117839747-A | Styrene epoxidation supported molybdenum catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-11617369-B2 | Antimicrobial gallium compounds and methods | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-04-04 | — | — | US | disclosed |
| CN-114203325-A | Preparation method of wide-bandgap oxide Schottky junction beta nuclear battery unit | 西安电子科技大学芜湖研究院 | 2022-03-18 | — | — | CN | disclosed |
| CN-113509950-A | Preparation method of gallium-based catalyst taking alumina modified by non-metallic elements as carrier | 福州大学 | 2021-10-19 | — | — | CN | disclosed |
| US-20200390104-A1 | ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-12-17 | — | — | US | disclosed |
| US-20200331807-A1 | HIGH PERMEABLE ZIRCONIA BLANK CAPABLE OF SINTERING AT HIGH SPEED | SHOFU INC. (JP) | 2020-10-22 | — | — | US | disclosed |
| EP-3712121-A1 | HIGH PERMEABLE ZIRCONIA BLANK CAPABLE OF SINTERING AT HIGH SPEED | Shofu Inc. (JP) | 2020-09-23 | — | — | EP | disclosed |
| CN-111454056-A | High-permeability zirconia blank for high-speed sintering | 株式会社松风 | 2020-07-28 | — | — | CN | disclosed |
| WO-2019165425-A1 | ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11617369-B2 | Antimicrobial gallium compounds and methods | GSDMD, GLMN, GDA | TSHR 2925/4885ALDH1A1 4360/4885MEN1 643/4885 |
| US-20200390104-A1 | ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS | GSDMD, GLMN, GDA | TSHR 2925/4885ALDH1A1 4360/4885MEN1 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.