Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 7/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557685 | 0.82 | F12 (0.42) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL17861440 | 0.80 | CYP2A6 (0.50) | TERTAPPEGFRS100A4CNR2 | |
| SCHEMBL22186673 | 0.79 | TERT (0.46) | TERTAPPEGFRS100A4CNR2 | |
| SCHEMBL31868436 | 0.76 | NOS3 (0.53) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL3747200 | 0.76 | NOS3 (0.53) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL29508479 | 0.75 | F12 (0.57) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL5989271 | 0.75 | F12 (0.57) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL3180290 | 0.73 | PSMB5 (0.49) | TERTAPPADKS100A4CNR2 | |
| SCHEMBL29439792 | 0.72 | PLAU (0.56) | F12PLAUNCF1NOS3NOS1 | |
| SCHEMBL29987789 | 0.72 | MAP4K4 (0.54) | F12PLAUNCF1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111918961-B | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2023-10-24 | — | — | CN | claimed |
| CN-111918961-A | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2020-11-10 | — | — | CN | claimed |
| WO-2019189554-A1 | CARDIOMYOCYTE MATURATION PROMOTER | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | claimed |
| CN-111918961-B | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-111918961-B | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-111918866-B | Heterocyclic compounds | 千纸鹤治疗公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-111918866-A | Heterocyclic compounds | 国立大学法人京都大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-111918961-A | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-111918961-A | Myocardial cell maturation promoter | 国立大学法人京都大学 | 2020-11-10 | — | — | CN | disclosed |
| WO-2019189553-A1 | HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | disclosed |
| WO-2019189554-A1 | CARDIOMYOCYTE MATURATION PROMOTER | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | disclosed |