Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669368 | 0.93 | MEN1 (0.64) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL417622 | 0.91 | MAPT (0.55) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL21409923 | 0.90 | MEN1 (0.68) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL10002475 | 0.85 | ALDH1A1 (0.71) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL2686936 | 0.84 | NPC1 (0.54) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1655753 | 0.83 | MEN1 (0.73) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL30533210 | 0.83 | MEN1 (0.73) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL14669372 | 0.83 | NPC1 (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL2569383 | 0.82 | NPC1 (0.56) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30822560 | 0.82 | NPC1 (0.56) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189554-A1 | CARDIOMYOCYTE MATURATION PROMOTER | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | claimed |
| WO-2019189553-A1 | HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | disclosed |
| WO-2019189554-A1 | CARDIOMYOCYTE MATURATION PROMOTER | 国立大学法人京都大学 | 2019-10-03 | — | — | WO | disclosed |