Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.77 |
| ▸ | DDX5 | P17844 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312371 | 1.00 | TOP1 (1.00) | TOP1SLC2A1DDX5 | |
| SCHEMBL21450469 | 1.00 | TOP1 (1.00) | TOP1SLC2A1DDX5 | |
| Lurtotecan SCHEMBL19208 | 0.95 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29774186 | 0.95 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL13992 | 0.95 | TOP1 (1.00) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649335 | 0.95 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL29379042 | 0.95 | TOP1 (0.98) | TOP1SLC2A1 | |
| Lurtotecan SCHEMBL1649336 | 0.94 | TOP1 (0.97) | TOP1SLC2A1 | |
| SCHEMBL25402218 | 0.93 | TOP1 (0.87) | TOP1SLC2A1 | |
| SCHEMBL23255613 | 0.93 | TOP1 (0.87) | TOP1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189419-A1 | ANTI-CANCER AGENT-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2019-10-03 | — | — | WO | claimed |
| WO-2019189419-A1 | ANTI-CANCER AGENT-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2019-10-03 | — | — | WO | disclosed |