⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895544 | 0.75 | — | — | |
| SCHEMBL10951521 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL10951520 | 0.75 | ALDH1A1 (0.31) | — | |
| Isovaleramide SCHEMBL6055503 | 0.73 | ALDH1A1 (0.53) | — | |
| Isovaleramide SCHEMBL9641 | 0.73 | — | — | |
| SCHEMBL4100933 | 0.73 | — | — | |
| SCHEMBL11846426 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL28141404 | 0.71 | — | — | |
| Isovaleramide SCHEMBL1650316 | 0.71 | — | — | |
| Isovaleramide SCHEMBL9846971 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| US-20240025886-A1 | INHIBITORS OF IGF2BP1-RNA BINDING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-01-25 | — | — | US | disclosed |
| CN-115786703-A | Method for extracting mineral ions by using inorganic porous material loaded with ionic liquid | 吉林大学 | 2023-03-14 | — | — | CN | disclosed |
| US-20200125564-A1 | NOVEL NK-3 RECEPTOR SELECTIVE ANTAGONIST COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN NK-3 RECEPTORS MEDIATED DISORDERS | OGEDA SA (BE) | 2020-04-23 | — | — | US | disclosed |
| EP-3628676-A1 | MODIFIED PEPTIDES AND THEIR USES | Université de Montpellier (FR) | 2020-04-01 | — | — | EP | disclosed |
| US-10544150-B2 | NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders | OGEDA SA (BE) | 2020-01-28 | — | — | US | disclosed |
| US-10065960-B2 | NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders | OGEDA SA (BE) | 2018-09-04 | — | — | US | disclosed |
| US-20180194772-A1 | NOVEL NK-3 RECEPTOR SELECTIVE ANTAGONIST COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN NK-3 RECEPTORS MEDIATED DISORDERS | OGEDA SA (BE) | 2018-07-12 | — | — | US | disclosed |
| US-9926325-B2 | NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders | OGEDA SA (BE) | 2018-03-27 | — | — | US | disclosed |
| EP-1190071-A2 | 17867, A NOVEL HUMAN AMINOPEPTIDASE | Millennium Pharmaceuticals, Inc. (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6362324-B1 | USED AS TARGET FOR DIAGNOSIS AND TREATMENT IN AMINOPEPTIDASE-RELATED DISORDERS SUCH AS AGING, CANCERS, CATARACTS, CYSTIC FIBROSIS AND LEUKEMIAS; USED IN DRUG-SCREENING TO IDENTIFY AGONISTS, ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. | 2002-03-26 | — | — | US | disclosed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2001036605-A2 | 2786, A HUMAN AMINOPEPTIDASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001023590-A2 | 22196, A NOVEL HUMAN AMINOPEPTIDASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-04-05 | — | — | WO | disclosed |
| WO-2001000811-A2 | 17867, A NOVEL HUMAN AMINOPEPTIDASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-RE29843-E | Substituted thiazoles and flavoring processes and products produced thereby | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |