Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414342 | 0.86 | RAB9A (0.55) | HRH3ACHEKMT2AMCHR1HTR2A | |
| SCHEMBL20038328 | 0.83 | HRH3 (0.48) | HRH3ACHEKMT2AMCHR1CHRM1 | |
| SCHEMBL22876983 | 0.83 | KMT2A (0.42) | HRH3KMT2ACYP2D6CYP1A2MEN1 | |
| SCHEMBL12504038 | 0.81 | HRH3 (0.56) | HRH3ACHEKMT2ALTA4HCYP2D6 | |
| SCHEMBL20356732 | 0.81 | HRH3 (0.62) | HRH3KMT2ACYP2D6CYP1A2MEN1 | |
| SCHEMBL21414363 | 0.80 | ALDH1A1 (0.55) | HRH3KMT2ACYP2D6CYP1A2MEN1 | |
| SCHEMBL18291525 | 0.80 | HRH3 (0.48) | HRH3ACHEKMT2AMCHR1CHRM1 | |
| SCHEMBL20037827 | 0.80 | HRH3 (0.48) | HRH3ACHEKMT2AMCHR1CHRM1 | |
| SCHEMBL21414343 | 0.80 | CXCR4 (0.49) | HRH3KMT2ACHRM1CYP2D6CYP1A2 | |
| SCHEMBL20249125 | 0.80 | HRH3 (0.45) | HRH3ACHEKMT2AMCHR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3546458-A1 | PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2019-10-02 | — | — | EP | disclosed |