Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20172394 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL3423327 | 0.80 | MAPT (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL11884986 | 0.80 | ACHE (0.37) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL24055879 | 0.79 | AHR (0.59) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL20308132 | 0.79 | ACHE (0.45) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL17490209 | 0.79 | KDM4E (0.58) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL11884994 | 0.77 | IDO1 (0.41) | ROCK2 | |
| SCHEMBL431566 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL10431605 | 0.75 | AHR (0.59) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL30521901 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339395-B1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2019-10-02 | — | — | EP | disclosed |