Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431605 | 0.89 | AHR (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11093267 | 0.87 | MAPT (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11093097 | 0.87 | AHR (0.62) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11093395 | 0.82 | PIM1 (0.42) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL21415334 | 0.80 | KDM4E (0.36) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11748674 | 0.78 | AHR (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL24786939 | 0.74 | NOS1 (0.34) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL20172125 | 0.74 | MEN1 (0.38) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15440145 | 0.74 | MAPT (0.59) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL377454 | 0.73 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163692-A1 | AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2009-06-25 | — | — | US | claimed |
| EP-2209156-A1 | Composite membrane and method for making | General Electric Company (US) | 2010-07-21 | — | — | EP | disclosed |
| US-20100167100-A1 | COMPOSITE MEMBRANE AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY | 2010-07-01 | — | — | US | disclosed |
| US-20090163692-A1 | AROMATIC POLYETHERS | GENERAL ELECTRIC COMPANY (US) | 2009-06-25 | — | — | US | disclosed |