SCHEMBL2141548

SCHEMBL2141548

O=C(O)CCCCC(C(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
NFKB1 P19838 2/20 0.58
TSHR P16473 1/20 0.58
PMP22 Q01453 1/20 0.58
GSTK1 Q9Y2Q3 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.53
ENPEP Q07075 1/20 0.52
FFAR4 Q5NUL3 2/20 0.50
FFAR1 O14842 2/20 0.50
ALDH1A1 P00352 1/20 0.48
GPR84 Q9NQS5 1/20 0.48
AKR1B1 P15121 1/20 0.48
CYP2D6 P10635 1/20 0.48
FOLH1 Q04609 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27837396 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL15346300 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL10417268 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL289697 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL6382669 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL18491280 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL4807149 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL7913017 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL7910158 0.97 TSHR (0.63) LMNANFKB1TSHRPMP22GSTK1
SCHEMBL2797202 0.92 LMNA (0.56) LMNANFKB1TSHRPMP22GSTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003057154-A2 NAALADASE INHIBITORS FOR TREATING HUNTINGTON'S DISEASE GUILDFORD PHARMACEUTICALS INC. (US) 2003-07-17 WO claimed
WO-2001091738-A2 NAALADASE INHIBITORS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS GUILFORD PHARMACEUTICALS INC. (US) 2001-12-06 WO claimed
CN-110402511-B Binder composition for secondary battery 日本电气株式会社 2024-06-18 CN disclosed
US-11982055-B2 Creping adhesives and processes for making and using same ECOLABS USA INC. (US) 2024-05-14 US disclosed
US-20240150967-A1 CREPING ADHESIVES AND PROCESSES FOR MAKING AND USING SAME ECOLAB USA INC. (US) 2024-05-09 US disclosed
EP-3313951-B1 CREPING ADHESIVES CONTAINING FUNCTIONALIZED CROSSLINKED RESINS ECOLAB USA INC (US) 2023-11-29 EP disclosed
WO-2023212501-A1 CREPING ADHESIVES COMPRISING POLYELECTROLYTE COMPLEX ECOLAB USA INC. (US) 2023-11-02 WO disclosed
US-20230349103-A1 CREPING ADHESIVES COMPRISING POLYELECTROLYTE COMPLEX ECOLAB USA INC. (US) 2023-11-02 US disclosed
US-11591452-B2 Emulsifier particles and methods for making and using same INGEVITY SOUTH CAROLINA, LLC (US) 2023-02-28 US disclosed
EP-3873966-A1 NOVEL POLYGLYCOLIC ACID AND PREPARATION METHOD THEREOF BY POLYCONDENSATION Pujing Chemical Industry Co., Ltd (CN) 2021-09-08 EP disclosed
US-11018342-B2 Binder composition for secondary battery NEC CORPORATION (JP) 2021-05-25 US disclosed
US-5081135-A Bactericides ROUSSEL UCLAF (FR) 1992-01-14 US disclosed
EP-0253007-A1 Stabilized polymers, novel stabilizers, and synthesis thereof The B.F. GOODRICH Company (US) 1988-01-20 EP disclosed
US-4647683-A Preparing ester containing organosilicon compounds (SWC) STAUFFER-WACKER SILICONES CORPORATION (US) 1987-03-03 US disclosed
US-4601839-A A-AMINOACETAMIDES THE B. F. GOODRICH COMPANY (US) 1986-07-22 US disclosed
US-4310429-A HEAT AND OXIDATION RESISTANT AMINOACETAMIDES THE B. F. GOODRICH COMPANY (US) 1982-01-12 US disclosed
US-4237270-A ANTITUMOR AGENTS SPOFA, UNITED PHARMACEUTICAL WORKS (CS) 1980-12-02 US disclosed
US-RE29131-E CURED TO PROTECTIVE COATINGS UNION CARBIDE CORPORATION (US) 1977-02-01 US disclosed
US-3990180-A Peat containers for the planting of containerized seedlings BUNTING WILLIAM M 1976-11-09 US disclosed
US-3931058-A POLYGLYCIDYL COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND USE CIBA-GEIGY AG (CH) 1976-01-06 US disclosed