Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346300 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL289697 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL27837396 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL18491280 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL10417268 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL6382669 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL7913017 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL7910158 | 1.00 | TSHR (0.63) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL2141548 | 0.97 | LMNA (0.61) | TSHRLMNANFKB1PMP22GSTK1 | |
| SCHEMBL31389992 | 0.90 | TSHR (0.57) | TSHRLMNANFKB1PMP22GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282551-B2 | Thermoplastic block copolymers consisting of polyalkyl(meth)acrylate and polyamide segments and the use thereof | EMS-CHEMIE AG (CH) | 2007-10-16 | — | — | US | claimed |
| US-20240066132-A1 | NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | NOVARTIS AG (CH) | 2024-02-29 | — | — | US | disclosed |
| US-11752211-B2 | Fatty acids and their use in conjugation to biomolecules | NOVARTIS AG (CH) | 2023-09-12 | — | — | US | disclosed |
| CN-115135484-A | Powder bed fusion printing system using polyarylene sulfide powder | 提克纳有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-115135482-A | Three-dimensional printing system employing toughened polyarylene sulfide compositions | 提克纳有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-3988170-A1 | FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | Novartis AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| US-20210000964-A1 | NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20190000923-A1 | METHODS OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GROWTH DIFFERENTIATION FACTOR 15 (GDF-15) | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-01-03 | — | — | US | disclosed |
| WO-2017109706-A1 | METHODS OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GROWTH DIFFERENTIATION FACTOR 15 (GDF-15) | NOVARTIS AG (CH) | 2017-06-29 | — | — | WO | disclosed |
| US-20170119851-A1 | METHODS OF TREATING ANOREXIA | NOVARTIS AG (CH) | 2017-05-04 | — | — | US | disclosed |
| US-7166398-B2 | Electrophotographic photoreceptor and device | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-7078159-B2 | Method for the preparation of a printing plate | EASTMAN KODAK COMPANY (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050064318-A1 | Image forming apparatus and image forming method | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| US-20040259009-A1 | Electrophotographic photoreceptor and device | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1386729-A1 | Method for the preparation of a printing plate | EASTMAN KODAK COMPANY (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20040018447-A1 | Method for the preparation of a printing plate | EASTMAN KODAK COMPANY | 2004-01-29 | — | — | US | disclosed |
| US-20030104234-A1 | Polyester carbonate and a data carrier therefrom | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
| US-6203914-B1 | PROTECTIVE SHEETS FOR CYLINDERS WITH FLEXIBLE BASES AND BALLS WITH CONVEX PORTIONS EXPOSED | SHINODA & CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-5902709-A | BRANCHED POLYESTER HAVING SPECIFIED TETRAHYDROFURAN-INSOUBLE CONTENT, MOLECULAR WEIGHT DISTRIBUTION | TOMOEGAWA PAPER CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-4487895-A | Powdered mixture of polyamides for heat sealing by the powder point process | Chemische Werke H/u/ ls AG (DE) | 1984-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119851-A1 | METHODS OF TREATING ANOREXIA | CRH, VIP, GIPR | TSHR 163/4885LMNA 4627/4885NFKB1 3985/4885 |
| US-20240066132-A1 | NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | FABP1, FABP2, FABP3 | TSHR 828/4885LMNA 1459/4885NFKB1 1106/4885 |
| US-11752211-B2 | Fatty acids and their use in conjugation to biomolecules | FABP1, FABP2, FABP3 | TSHR 620/4885LMNA 1424/4885NFKB1 1285/4885 |
| US-20190000923-A1 | METHODS OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GROWTH DIFFERENTIATION FACTOR 15 (GDF-15) | HDGF, FABP1, GLS2 | TSHR 710/4885LMNA 2414/4885NFKB1 1563/4885 |
| US-20210000964-A1 | NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES | FABP1, FABP2, FABP3 | TSHR 828/4885LMNA 1459/4885NFKB1 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.