Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015428 | 0.83 | FGFR1 (0.35) | GAAGFERHTR6KMT2AKDM4E | |
| SCHEMBL20460091 | 0.78 | GAA (0.35) | GAAGFERKMT2AKDM4EFGFR1 | |
| SCHEMBL20861097 | 0.78 | MAPT (0.34) | GAAGFERSIGMAR1HTR6KMT2A | |
| SCHEMBL26186455 | 0.74 | RAB9A (0.34) | GAAGFERKMT2AKDM4EMAPT | |
| SCHEMBL20860950 | 0.74 | KDM4E (0.42) | GAAGFERSIGMAR1HTR6KMT2A | |
| SCHEMBL22477412 | 0.73 | MAT2A (0.33) | GAAPTGDR2KMT2AKDM4EFGFR1 | |
| SCHEMBL21913554 | 0.70 | PTGDR2 (0.35) | PTGDR2HTR6KMT2AKDM4EADRA2A | |
| SCHEMBL24797463 | 0.70 | KDM4E (0.39) | GAASIGMAR1KMT2AKDM4EMAPT | |
| SCHEMBL679015 | 0.69 | KDM4E (0.56) | GAAGFERKMT2AKDM4EFGFR1 | |
| SCHEMBL12844422 | 0.68 | KMT2A (0.32) | GAAKMT2ALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174885-B1 | 2,9-FUNCTIONALIZED BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES AS HOSTS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | IDEMITSU KOSAN CO (JP) | 2019-10-02 | — | — | EP | disclosed |