Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280519 | 1.00 | ACHE (0.35) | ACHE | |
| SCHEMBL18790863 | 0.86 | IDO1 (0.34) | — | |
| SCHEMBL21419598 | 0.86 | ACHE (0.36) | ACHE | |
| SCHEMBL2935859 | 0.76 | ACHE (0.37) | ACHE | |
| SCHEMBL12854187 | 0.76 | PGR (0.32) | — | |
| SCHEMBL25141974 | 0.74 | IDO1 (0.36) | — | |
| SCHEMBL20333327 | 0.74 | — | — | |
| SCHEMBL18755609 | 0.74 | ACHE (0.36) | ACHE | |
| SCHEMBL20926022 | 0.74 | CYP19A1 (0.40) | ACHE | |
| SCHEMBL21480920 | 0.72 | IDO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190300509-A1 | MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF | UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" (IT) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190300509-A1 | MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF | STIM1, ORAI1, SARAF | ACHE 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.