Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422281 | 0.85 | PAOX (0.38) | APOBEC3AAPOBEC3GPAOXALDH1A1GAA | |
| SCHEMBL1147864 | 0.80 | PAOX (0.47) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| SCHEMBL164414 | 0.78 | PAOX (0.66) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| SCHEMBL177754 | 0.78 | NPSR1 (0.47) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| SCHEMBL149151 | 0.78 | AKR1B1 (0.50) | PAOXALDH1A1KDM5AKDM4CLMNA | |
| SCHEMBL21391387 | 0.76 | PAOX (0.44) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL9078509 | 0.76 | KDM5A (0.49) | PAOXALDH1A1KDM5AKDM4CLMNA | |
| SCHEMBL3933480 | 0.76 | PAOX (0.44) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| SCHEMBL25529753 | 0.76 | ALDH1A1 (0.54) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 | |
| SCHEMBL26353796 | 0.76 | APOBEC3A (0.47) | APOBEC3AAPOBEC3GPAOXALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190298681-A1 | Nanoliposomal Targeting of Ephrin Receptor A2 (Epha2) and Related Diagnostics | MERRIMACK PHARMACEUTICALS, INC. | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190298681-A1 | Nanoliposomal Targeting of Ephrin Receptor A2 (Epha2) and Related Diagnostics | EPHA2, EPHB2, EPHB1 | APOBEC3A 3448/4885APOBEC3G 3251/4885PAOX 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.