Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21410145 | 0.88 | BRD4 (0.77) | BRD4SMN1; SMN2ALDH1A1MEN1PABPC1 | |
| SCHEMBL7167441 | 0.88 | BRD4 (1.00) | BRD4SMN1; SMN2ALDH1A1MEN1TSHR | |
| SCHEMBL22916953 | 0.86 | BRD4 (0.73) | BRD4SMN1; SMN2ALDH1A1MEN1PABPC1 | |
| SCHEMBL21410459 | 0.85 | BRD4 (0.76) | BRD4SMN1; SMN2ALDH1A1MEN1TSHR | |
| SCHEMBL23174938 | 0.82 | BRD4 (0.67) | BRD4SMN1; SMN2ALDH1A1MEN1PABPC1 | |
| SCHEMBL21410242 | 0.82 | BRD4 (0.67) | BRD4SMN1; SMN2ALDH1A1TP53KDM4E | |
| SCHEMBL21410434 | 0.81 | BRD4 (0.66) | BRD4SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL22973287 | 0.78 | BRD4 (0.61) | BRD4TP53HPGDHDAC1HDAC6 | |
| SCHEMBL21423952 | 0.78 | L3MBTL1 (0.57) | BRD4SMN1; SMN2ALDH1A1MEN1PABPC1 | |
| SCHEMBL5697129 | 0.77 | BRD4 (0.71) | BRD4SMN1; SMN2ALDH1A1MEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |