Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697188 | 0.85 | BRD4 (0.72) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL7167441 | 0.83 | BRD4 (1.00) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL21423949 | 0.77 | BRD4 (0.79) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL21410145 | 0.76 | BRD4 (0.77) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL22916953 | 0.74 | BRD4 (0.73) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL21410459 | 0.73 | BRD4 (0.76) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL7646032 | 0.71 | BRD4 (0.72) | BRD4HPGDLMNAALDH1A1TSHR | |
| SCHEMBL23174938 | 0.71 | BRD4 (0.67) | BRD4HPGDALDH1A1TSHRMEN1 | |
| SCHEMBL21410242 | 0.71 | BRD4 (0.67) | BRD4HPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21410434 | 0.70 | BRD4 (0.66) | BRD4HPGDLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100492-B1 | INDOLE sPLA2 INHIBITORS | LILLY CO ELI (US) | 2006-05-24 | — | — | EP | disclosed |